Robert E. Burke, MD
The Alfred and Minnie Bressler Professor of Neurology and Pathology & Cell Biology
Director of Research Laboratories for Parkinson's Disease and Related Disorders
Research Laboratories for Parkinson's Disease
» Division of Parkinson's Disease and Other Movement Disorders
» Department of Neurology
» Recent Publications
Dr. Burke's research focus is on basic neuroscience related to the cause and pathogenesis of movement disorders, particularly Parkinson's Disease. He demonstrated that a genetically programmed form of cell death, called apoptosis, occurs in dopaminergic neurons of the substantia nigra. This form of cell death can be induced in models of injury to explain the pathogenesis of parkinsonism and other movement disorders, including Huntington's Disease. Ongoing efforts are aimed towards understanding this form of cell death at the molecular level, and preventing it with growth factors. Dr. Burke's clinical research includes important work in dystonia and the tardive dyskinesias, and has led to the first descriptions of the delayed-onset dystonias and tardive dystonia. Dr. Burke's publications have appeared in The Journal of Neuroscience, The Journal of Comparative Neurology, The Proceedings of the National Academy of Sciences (USA), Nature Neuroscience and other leading neuroscience journals Dr. Burke's laboratory website can be directly visited.