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Yaakov Stern, PhD
Professor of Clinical Neuropsychology
Insurance: Medicare
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Research:
Cognitive Neuroscience Division - www.cogneurosci.org
Taub Institute - www.taubinstitute.org
The Gertrude H. Sergievsky Center - cpmcnet.columbia.edu/dept/sergievsky
Lucy G. Moses Center for Memory and Behavioral Disorders - http://cpmcnet.columbia.edu/dept/neurology/memory/
Yaakov Stern is a Professor of Clinical Neuropsychology in the Departments of Neurology, Psychiatry, and Psychology, as well as the in Sergievsky Center and the Taub Institute for the Research on Alzheimer's Disease and the Aging Brain, at Columbia University College of Physicians and Surgeons. Dr. Stern directs the Cognitive Neuroscience Division of the Sergievsky Center and is Director of Neuropsychology for the Memory Disorders Clinic at the New York State Psychiatric Institute. He also directs the post-doctoral training program Neuropsychology and Cognition in Aging.
Ongoing Research:
Cognitive Reserve: I am interested in understanding the basis for individual differences in task performance in general, and more specifically, the reason why some individuals show more cognitive deficit than others given the same degree of brain pathology. Ongoing fMRI studies are designed to explore this issue using activation paradigms that carefully control for task difficulty and evaluating differential expression of brain networks across young and old healthy individuals and patients with Alzheimer's disease.
Cognitive Consequences of Sleep Deprivation: In parallel studies, we are exploring the neural basis for differential sensitivity to the cognitive effects of sleep deprivation. We have identified brain networks whose expression during task performance is affected by sleep deprivation. Individuals demonstrating greater changes in these networks have more pronounced cognitive changes. In collaborative studies, we have found that transcranial magnetic stimulation to key nodes in this network can improve task performance.
Heterogeneity of Alzheimer's disease: A prospective study is designed to explore individual differences in the rate of decline and in the manifestation of cognitive, behavioral, psychiatric and neurologic features in AD patients. Ongoing clinicopathologic studies should give insight into this heterogeneity.
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© 2004 The Neurological Institute of New York • 710 W 168th St, New York, NY 10032
Department of Neurology | Columbia University Medical Center | Last updated:
August 28, 2009
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